Tag Archives: Studies

Study identifies six different “types” of COVID-19 – CBS News

>The new, weird symptoms associated with Covid-19 – Daily Nation

The six categories are defined by different clusters of symptoms, and some patients in some groups are much more likely to need ventilators.

Full story of excerpts at Source Link: >Study identifies six different “types” of COVID-19 – CBS News

“A new study of COVID-19, based on data from a symptom tracker app, determined that there are six distinct “types” of the disease involving different clusters of symptoms. The discovery could potentially open new possibilities for how doctors can better treat individual patients and predict what level of hospital care they would need.

“The six clusters of symptoms outlined in the study are:

Flu-like with no fever: Headache, loss of smell, muscle pains, cough, sore throat, chest pain, no fever.

Flu-like with fever: Headache, loss of smell, cough, sore throat, hoarseness, fever, loss of appetite.

Gastrointestinal: Headache, loss of smell, loss of appetite, diarrhea, sore throat, chest pain, no cough.

Severe level one, fatigue: Headache, loss of smell, cough, fever, hoarseness, chest pain, fatigue.

Severe level two, confusion: Headache, loss of smell, loss of appetite, cough, fever, hoarseness, sore throat, chest pain, fatigue, confusion, muscle pain.

Severe level three, abdominal and respiratory: Headache, loss of smell, loss of appetite, cough, fever, hoarseness, sore throat, chest pain, fatigue, confusion, muscle pain, shortness of breath, diarrhea, abdominal pain.

“The first level, “flu-like with no fever,” is associated with headaches, loss of smell, muscle pains, cough, sore throat and chest pain. Patients at this level have a 1.5% chance of needing breathing support such as oxygen or a ventilator.

“The most severe type of COVID-19 is referred to as “severe level three, abdominal and respiratory,” and has all the above symptoms along with abdominal pain, shortness of breath and diarrhea. Nearly 20% of these patients need breathing support.

“Those are the severe level threes who wind up on a ventilator, and then it is touch-and-go as to whether they survive the infection entirely. Patients in the severe clusters also tended to be older or with pre-exisiting conditions and weakened immune systems, compared to those in the first three. 

“Scientists hope the discovery, once further studied, could help predict what types of care patients with COVID-19 might need, and give doctors the ability to predict which patients would fall into which category.

Continue reading full story at source link above.

Amazing Wisdom Quote ~ Knowledge comes from learning ...

 

Does Wearing a Mask Protect Me? Some Evidence Says Yes – The New York Times

>13 min podcast Wearing A Mask Could Be Even More Important Than We Thought : NPR One

People wearing face coverings will take in fewer coronavirus particles, evidence suggests, making disease less severe.

Full story of excerpts below at Source >Masks May Reduce Viral Dose, Some Experts Say

“as cases continue to rise across the country, experts are pointing to an array of evidence suggesting that masks also protect the people wearing them, lessening the severity of symptoms, or in some instances, staving off infection entirely.

“two researchers formally noted that mice exposed to larger quantities of germs were more likely to die. More recently, scientists have gone as far as to puff different amounts of a flu virus up the noses of human volunteers. The more virus in this nasal plume, they found, the likelier the participants were to get infected and experience symptoms.

Continue full story at source link above

Love this quote. We have a shared responsibility to protect ...

 

The Pandemic Is Pushing Scientists To Rethink How They Read Research Papers – NPR

>Factcheck – A Guide to Our Coronavirus Coverage

>Guide to Online Health Information 16 minute learning activity

>Snopes Factchecking Medical Section

>Newsguard COVID-19 Misinformation Resources

>Health Feedback Scientists Sorting Fact from Fiction

>Patient Advisor posts tag: Misinformation

“The coronavirus pandemic has posed a special challenge for scientists: Figuring out how to make sense of a flood of scientific papers from labs and scientists unfamiliar to them.

Read full story at source: >The Pandemic Is Pushing Scientists To Rethink How They Read Research Papers

“More than 6,000 coronavirus-related preprints from researchers around the world have been posted since the pandemic began, without the usual peer review as a quality check. Some are poor quality, while others, including papers from China from early in the course of the epidemic, contain vital information.

It takes a large investment of attention and effort to really dig deeply into a manuscript to scrutinize the methods, the claims and the relationship between the methods and the claims

“In the case of the hydroxychloroquine study… the reported results had veered significantly from their previously stated experimental plan. “Those struck me as a lot of major red flags…It probably took me something between 15 minutes and 30 minutes to come to the conclusion that this paper wasn’t worth the time of day. Sure enough, the promise of hydroxychloroquine as a COVID-19 treatment eventually crumbled, as several larger studies failed to show any benefit.

One way researchers are working to overcome bias is by coming together to form international research teams... Motivated by a desire to address “a common threat to humanity”

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Coronavirus can float in air — and experts say WHO and CDC should tell people that | KTLA

>NPR 10 minute podcast: Scientists Debate How Coronavirus Spreads, Experts Push For Mask Mandate

>The Scientists Debate: Is COVID-19 transmitted by airborne aerosols?

>Major News Outlets: Is COVID Airborne? 239 Scientists Say Evidence Shows It Is, Urge WHO, CDC To Alter Recommendations

“Most public health organizations, including the World Health Organization, do not recognize airborne transmission except for aerosol-generating procedures performed in healthcare settings. Hand washing and social distancing are appropriate, but in our view, insufficient to provide protection from virus-carrying respiratory microdroplets released into the air by infected people,”

‘They don’t want to talk about airborne transmission because that is going to make people afraid’

Read full story at Source: >Coronavirus can float in air — and experts say WHO and CDC should tell people that | KTLA

“Studies by the signatories and other scientists have demonstrated beyond any reasonable doubt that viruses are released during exhalation, talking, and coughing in microdroplets small enough to remain aloft in air and pose a risk of exposure at distances beyond 1 to 2 meters (yards) from an infected individual,”

“For example, at typical indoor air velocities, a 5 nanometre droplet will travel tens of meters, much greater than the scale of a typical room, while settling from a height of 1.5 metres (about five feet) to the floor.” What’s not clearly understood is how important droplet size is to coronavirus transmission,

“A lot of people crowded close together indoors where it is poorly ventilated — that is what drives the pandemic,” … A loud bar, where people must raise their voices to be heard, is a perfect storm of close contact, poor air circulation and people generating a lot of virus-carrying particles by talking, laughing and shouting.

Advice to avoid coronavirus transmission:

“I am very much concerned about the general public and schools and ventilation in school buildings and in dorms on college campuses and in bars and in churches and where people sing and where people congregate,” 

• Provide sufficient and effective ventilation (supply clean outdoor air, minimize recirculating air) particularly in public buildings, workplace environments, schools, hospitals and age care homes.

• Supplement general ventilation with airborne infection controls such as local exhaust, high efficiency air filtration, and germicidal ultraviolet lights. (These would be placed high up in the ceiling to avoid damage to people’s eyes and skin)

• Avoid overcrowding, particularly in public transport and public buildings.

“Such measures are practical and often can be easily implemented; many are not costly, For example, simple steps such as opening both doors and windows can dramatically increase air flow rates in many buildings…In buildings, carbon dioxide monitors can help managers know if the air is being refreshed properly.

“In a car, open windows and make sure the air conditioning or heat is not recirculated but set to include outside air.

Continue reading full story at source link above.

Do probiotics actually do anything? – 60 Minutes – CBS News

microbiomesnapshot0.jpg

Probiotics, manufactured mixtures of “good bacteria” that help digest food, have become a growing multibillion-dollar industry. But do they work?

13 Minute newscast and Full story at Source: >Do probiotics actually do anything? – 60 Minutes – CBS News

“There is an invisible universe hidden inside your body, it’s called the gut microbiome — a vast array of trillions of intestinal bacteria, hundreds of different species. They help digest your food in exchange for a warm, safe place to live. And we are only now starting to discover the gut microbiome plays a much larger role in our lives than we ever imagined.

“Some of those bacteria found inside us are replicated in commercially manufactured mixtures called “probiotics.” You see them on grocery and pharmacy shelves, and they’re recommended by your friends and often, by doctors like me.

“But do probiotics actually do anything?  To find out, first you need to know about the gut microbiome. (Continue at video and source link above)

“Right now, the microbiome is an area of hot research. Doctors are already treating illness by manipulating gut bacteria. A potentially life-threatening infection of the colon called C. Diff. has been successfully treated by moving bacteria from the gut of a healthy person to the gut of somebody who’s sick.

“And millions of people are trying to improve their microbiomes themselves using probiotics, so-called “good bacteria.” But here’s the problem: there’s a lot of conflict among scientists about whether probiotics provide any benefit at all.

“Dr. Hibberd has reviewed hundreds of studies in the medical literature about probiotics. She has also done her own studies and told us there’s not enough high quality research to recommend off-the-shelf probiotics for the medical problems for which they’re commonly used. 

Dr. Patricia Hibberd: The whole idea that maybe throwing in good bacteria that we would take by mouth that hopefully would land in the right places in the GI tract and work with the immune system. We just don’t know how to do any of that.

“Restoring that balance of bacteria in the gut microbiome is just one goal touted by makers of probiotics, a $50 billion global industry sold to us in capsules, popsicles, cereal, tea and some yogurt. And we’re told probiotics can even help your dog.

“One cause of confusion may be the placebo effect: some people using probiotics may feel better because they expect to feel better. And figuring out what probiotics do inside the gut is complicated. One reason is that each person’s microbiome is unique, so the same probiotic may have different effects on different people

“The researchers collected thousands of samples from a small group of adult volunteers who were given probiotics. Eran Segal: We’ve actually looked across the entire gastrointestinal tract at places where nobody has looked before. The volunteers all underwent multiple endoscopies and colonoscopies. ..so the results were actually very striking so what we’re seeing is that half the people take the probiotics and the probiotics, as they go in, they just go out and they don’t populate the gut.

“The researchers also studied a treatment commonly recommended by doctors, giving probiotics to help restore the balance of gut bacteria wiped out by antibiotics. Eran Segal: We found that the probiotics actually delayed the restoration of the bacteria of those individuals to what they had before as compared to individuals who took antibiotics and then did nothing.

“Despite disagreement about how or whether today’s probiotics work, every scientist we spoke with was hopeful about the possibility of improving health by manipulating the microbiome. Last year, Dr. Gordon’s team reported that a special supplemental mixture of nutrients containing chickpeas, soy, bananas and peanuts can repair the damaged microbiome of malnourished infants.

(See much more of full story and video at source link above)

A Nation Of Magical Thinkers | Blog For Iowa

I first heard the term “magical thinking” on ‘What you need to know” ABC news daily series yesterday from Dr. Jenifer Ashton. The term is a medical term in psychology to describe illogical thought patterns which ignores new evidence that challenges current non-scientific theories that are really beliefs. — DH

Full story at Source: >A Nation Of Magical Thinkers | Blog For Iowa

“COVID-19 has revealed our societal failure to understand what evidence is and to respect how it works. National and local political leaders have made decisions that ignored the evidence. Members of the general public have proved slow to accept the evidence. Measures adopted to help flatten the curve have been met with virulent protests, despite the evidence that they are working.”

“We have become a nation of magical thinkers, making decisions based on what we hope is the case and whom we want to believe.  When confronted with opposing evidence, we do not engage with it. We dismiss it and stick a label on it: “fake,” “phony,” “biased,” etc. And then we mistake that label for evidence.”

 

Big WHO Mixup: Asymptomatic Vs Presymptomatic: How The Virus Spreads : NPR

“Scientists at the World Health Organization were having a virtual press conference, a normal thing they do, just giving updates on the virus and how it’s moving around the world. And then something kind of confusing happens.

10 minute podcast and read full transcript of podcast at Source: >Asymptomatic Vs Presymptomatic: How The Virus Spreads : Short Wave : NPR

“Maria Van Kerkhove, who’s one of WHO’s top epidemiologists…

“listening to Van Kerkhove, you’d think – well, why did we lock down? Why do we wear masks? She left listeners with the impression that anyone without symptoms had a low chance of spreading the virus. And that’s wrong. We know – and there’s documented evidence for this – that the virus can be spread by people without symptoms.

“So this statement was reported on by news outlets. You know, the WHO is a major global health organization. What they say matters. And that scientist, Maria Van Kerkhove had to kind of walk this back.

“There was a lot of reaction and pressure from researchers and the public. People were saying that it was confusing at best or actually wrong at worst.

this mix-up with the WHO was partly about a distinction between asymptomatic people and what scientists are calling pre-symptomatic people.

“Asymptomatic, which is the group that Van Kerkhove was referring to, these are coronavirus carriers who are infected but they never end up showing any symptoms. They feel fine the whole time. And then there’s another group called pre-symptomatic. And these are people who’ve been infected. They haven’t gotten sick yet, but they will. And they can definitely spread the virus, we think, up to three days before they start showing symptoms. There’s plenty of evidence for this.

“But here’s the catch. You can’t tell if someone is asymptomatic or pre-symptomatic until one of them starts showing symptoms. And even if there are asymptomatic people out there that seem to be transmitting the virus less, there are documented cases where it’s happened. So what Van Kerkhove says she meant to say is that she has not seen evidence that people who are truly asymptomatic are out there effectively spreading the virus to a lot of other people.

“if you’re not actively sick, if you’re not running your nose everywhere – spreading coronavirus seems to require situations where people are hanging out really close together, mostly indoors, and doing things that project their voice and breath and spread respiratory droplets. So it’s situations like singing in a choir or panting during a dance class at the gym or shouting to be heard in a nightclub. These are all activities that have reportedly led to virus transmission.

 

Huge Study Throws Cold Water on Antimalarials for COVID-19 | MedPage Today


“No support for continued use seen in analysis of 15,000 patients who got controversial drugs”

Full story of excerpts below at Source: >Huge Study Throws Cold Water on Antimalarials for COVID-19 | MedPage Today

“Chloroquine or hydroxychloroquine (HCQ), with or without an antibiotic, in hospitalized COVID-19 patients were associated with increased risk of death in the hospital and higher rates of arrhythmias, analysis of outcomes in nearly 100,000 patients indicated.

>Medical Reference: The Lancet

“This is the first large scale study to find statistically robust evidence that treatment with chloroquine or hydroxychloroquine does not benefit patients with COVID-19,” 

 

 

Remdesivir: What we know about the potential coronavirus treatment


>Google News Search Results (Last 24 hrs)

Full Story at Source: >Remdesivir: What we know about the potential coronavirus treatment

“A drug being developed to treat COVID-19, the disease caused by new coronavirus, is reportedly showing some promise but there’s no guarantee initial reports will lead to a commercially available treatment. Experts have been racing to find a treatment for the illness that’s killed more than 60,000 Americans and sickened more than 1 million.

“The experimental drug remdesivir has emerged as the first possible scientifically proven treatment. Early data from a global study released Wednesday found patients given remdesivir recovered faster and may be less likely to die. However, another study published the same day in the British medical journal The Lancet found no clinical benefits to the drug.

“Here’s what we know about the drug: What is remdesivir? Remdesivir is an experimental antiviral drug from the American biotech firm Gilead Sciences. It was originally tested as a treatment for Ebola and other coronaviruses including SARS and is now being tested as a possible COVID-19 treatment.

“The drug impairs the ability of the virus to replicate, … “You’re decreasing the degree of infection so the immune system can fight. It’s like taking fuel away from the fire,” he said.Dr. Aneesh Mehta, lead investigator for the portion of the remdesivir trial at Emory University in Atlanta, stressed the drug and other antivirals are not “silver bullets” that immediately get rid of an infection and the damage doesn’t just “all go away” when the virus is gone.

 

Arizona Man dies after taking malaria medication promoted by the President, in effort to prevent coronavirus | TheHill

Video Caption: Dr. Anthony Fauci said there is not enough evidence to support claims that hydrox-chloroquine is effective in combatting COVID-19.

>4 Minute Podcast: Malaria Drug In High Demand For Treating COVID-19 Despite Lack Of Evidence That It’s Effective

“Health care company Banner Health announced Monday that a patient had died and his wife was in critical condition after they apparently took an anti-malaria drug touted by President Trump as a possible cure for coronavirus without a doctor’s prescription.

“In a statement, the company urged Americans against taking drugs not prescribed for them in response to the coronavirus pandemic, which has sickened thousands of people across the country. The chemical, which is available in tablet form as an anti-malaria drug, is also used as a cleaning chemical.”

“A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate, an additive commonly used at aquariums to clean fish tanks. Within thirty minutes of ingestion, the couple experienced immediate effects requiring admittance to a nearby Banner Health hospital, ” the statement read.

The couple had read a fake article about the cleaning chemical.

“Most patients who become infected with COVID-19 will only require symptomatic care and self-isolation to prevent the risk of infecting others. Check first with a primary care physician. The routine use of specific treatments, including medications described as ‘anti-COVID-19’, is not recommended for non-hospitalized patients, including the anti-malarial drug chloroquine,” the statement continued.

“Trump tweeted about the use of chloroquine as an effective treatment for severe coronavirus cases over the weekend, urging Food and Drug Administration (FDA) officials to put it to use “immediately.” “HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains – Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents) be put in use IMMEDIATELY. PEOPLE ARE DYING, MOVE FAST, and GOD BLESS EVERYONE!” he tweeted.TAGS DONALD TRUMP CORONAVIRUS MALARIA

Read more at Source: >Man dies after taking malaria medication in effort to prevent coronavirus | TheHill